meaningful relationships with meaningless people

Do you think some people are incapable of meaningful relationships? I do.  From my experience, people that have not had the fortune of being raised by loving, meaningful parents, tend to have problems being able to co-facilitate a meaningful relationship. Does this mean they can never have a meaningful relationship? I have no idea.  I wish that were not the case, but so far 10 yrs of data says otherwise in my life.  The interesting part is my wife does seem to be able to have meaningful or relatively meaningful relationships with our children, but it's more of a peer type friendship than a parental type relationship.  Could it just be her general immaturity? Maybe. Interestingly enough a few days ago I was having a conversation with my daughter and laughing and joking and I realized that I could not have that same relationship with my wife because at every turn she refutes it.  Is there hope for me and her?  I am beginning to seriously doubt it.